Influence of STAT4 Polymorphism in Primary Sjögren’s Syndrome
نویسندگان
چکیده
منابع مشابه
STAT4 gene polymorphism in patients after renal allograft transplantation
INTRODUCTION STAT4 (signal transducer and activator of transcription 4) is involved in the regulation of innate and adaptive immune responses. Some studies have suggested that STAT4 may be involved in the immune response after graft transplantation. Several polymorphisms in the STAT4 gene have been identified. The most commonly studied polymorphism in the STAT4 gene is rs7574865. In our study, ...
متن کاملCTLA4 polymorphism and primary Sjögren's syndrome
The March 2007 issue of Arthritis Research and Therapy included a research article by Gottenberg and colleagues [1] that reports a failure to confirm our previous study [2] of a genetic association between CTLA4 and primary Sjögren's syndrome (pSS). Similar to our study, the Gottenberg study analysed both CTLA4 CT60 and +49A/G single nucleotide polymorphisms (SNPs). They observed an association...
متن کاملExpression Levels of PPARγ and CYP-19 in Polycystic Ovarian Syndrome Primary Granulosa Cells: Influence of ω-3 Fatty Acid
Background The omega-3 fatty acid (ω-3 fatty acid) such as eicosapentaenoic acid (EPA) is currently used in the clinic as a nutritional supplement in the treatment of polycystic ovarian syndrome (PCOS). The present study was designed to investigate the effect of EPA on the expression levels of peroxisome proliferator-activated receptor gamma (PPARγ) and cytochrome P450 aromatase (encoded by the...
متن کاملSTAT4 rs7574865 polymorphism and the susceptibility of systemic sclerosis (SSc)
Previous study suggested that signal transducers and activators of transcription-4 (STAT4) rs7574865 polymorphism may play an important role in susceptibility to Systemic Sclerosis (SSc) in Chinese. However, no further study was conducted to confirm this result. Thus, we did a case-control study. 174 SSc patients and 202 controls were enrolled in this study. When the STAT4 rs7574865 polymorphis...
متن کاملthe study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region
چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Rheumatology
سال: 2010
ISSN: 0315-162X,1499-2752
DOI: 10.3899/jrheum.091007